半岛bd体育手机客户端 介绍
基因名:
SLCO3A1 半岛bd体育手机客户端 别名: OATP-D; OATP-RP3; OATP3A1; OATPD; OATPRP3; SLC21A11; SLCO3A1; solute carrier organic anion transporter family member 3A1; solute carrier organic anion transporter family member 3A1; solute carrier organic anion transporter family member 3A1; PGE1 transporter; organic anion transporter polypeptide-related protein 3; organic anion-transporting polypeptide D; sodium-independent organic anion transporter D; solute carrier family 21 (organic anion transporter), member 11; solute carrier family 21 member 11; 可溶性载质转运蛋白3A1; 背景信息:
The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-D is a 710 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-D mediates the Na+-independent transport of vasopressin, prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II and other organic anions, but not estrone-3-sulfate, DPDPE, taurocholate, DHEAS or digoxin. OATP-D is ubiquitously expressed with highest levels present in leukocytes and spleen. OATP-D is expressed as four isoforms produced by alternative splicing events.
标签:His-tag |
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