蛋白质/抗原/多肽 >> 重组蛋白
重组MICAL样蛋白1
半岛bd体育手机客户端 介绍
基因名:
Micall1 半岛bd体育手机客户端 别名: AI448246; D15Mit260; D15N2e; EST573322; EST820961; MIRab13; mKIAA1668; Micall1; microtubule associated monooxygenase, calponin and LIM domain containing -like 1; microtubule associated monooxygenase, calponin and LIM domain containing -like 1; MICAL-like protein 1; microtubule associated monoxygenase, calponin and LIM domain containing -like 1; molecule interacting with Rab13; MICAL样蛋白1; 背景信息:
MIRAB13 is an 863 amino acid cytoplasmic protein belonging to the MICAL family that contains one CH (calponin-homology) domain, one LIM zinc-binding domain and two unique asparagine-proline-phenylalanine motifs, which are known to interact with EH-domains. Considered a cytoskeletal regulator, MIRAB13 associates with Rab 13, a tight junction protein, as well as EHD, a key regulator of ligand-induced endocytosis and recycling. MIRAB13 is encoded by a gene located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
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