蛋白质/抗原/多肽 >> 重组蛋白
重组FBXL21蛋白
半岛bd体育手机客户端 介绍
基因名：
FBXL21P 半岛bd体育手机客户端 别名： FBL3B； FBXL21； FBXL3B； FBXL3P； Fbl21； FBXL21P； F-box and leucine rich repeat protein 21, pseudogene； F-box and leucine rich repeat protein 21, pseudogene； F-box and leucine-rich repeat protein 21； F-box and leucine-rich repeat protein 3 pseudogene； F-box and leucine-rich repeat protein 3B； F-box protein Fbl3b； F-box/LRR-repeat protein 21； F-box/LRR-repeat protein 3B； FBXL21蛋白； 背景信息：
FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.
标签：His-tag |
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