蛋白质/抗原/多肽 >> 重组蛋白
重组Rab5激活蛋白6
半岛bd体育手机客户端 介绍
基因名:
GAPVD1 半岛bd体育手机客户端 别名: GAPEX5; GAPex-5; RAP6; GAPVD1; GTPase activating protein and VPS9 domains 1; GTPase activating protein and VPS9 domains 1; GTPase-activating protein and VPS9 domain-containing protein 1; Rab5 exchange factor; Rab5-activating protein 6; Rab5激活蛋白6; 背景信息:
GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
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