蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白318
半岛bd体育手机客户端 介绍
基因名:
ZNF318 半岛bd体育手机客户端 别名: HRIHFB2436; TZF; ZFP318; ZNF318; zinc finger protein 318; zinc finger protein 318; zinc finger protein 318; endocrine regulator; endocrine regulatory protein; testicular zinc finger; 锌指蛋白318; 背景信息:
ZNF318 is a 2279 amino acid endocrine regulatory protein that localizes to the nucleus. Highly expressed in testis, ovaries and kidneys, ZNF318 is a co-repressor of androgen receptor (AR)-mediated transcriptional activation and is thought to regulate transcription during spermatogenesis. ZNF318 interacts with the N-terminal domain of AR and contains two matrin-type zinc fingers. Two isoforms of ZNF318, designated TZF and TZF-L, are produced due to alternative splicing events. Each of these splice variants are thought to have unique roles in transcriptional regulation. While the TZF isoform functions as a repressor of AR-mediated transcriptional activation, the TZF-L isoform is thought to enhance AR-mediated transcriptional activation.
标签:His-tag |
相关半岛bd体育手机客户端
|