蛋白质/抗原/多肽 >> 重组蛋白
重组形态发生紊乱关联激活因子2蛋白
半岛bd体育手机客户端 介绍
基因名:
DAAM2 半岛bd体育手机客户端 别名: NPHS24; dJ90A20A.1; DAAM2; dishevelled associated activator of morphogenesis 2; dishevelled associated activator of morphogenesis 2; disheveled-associated activator of morphogenesis 2; 形态发生紊乱关联激活因子2; 蓬乱蛋白关联形态激活因子2(DAAM2); 背景信息:
DAAM2 is a widely expressed 1,068 amino acid protein that contains one DAD domain, one FH1 domain, one FH2 domain and one GBD domain, through which it may play a role in Wnt/Frizzled-associated signaling events. The gene encoding DAAM2 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
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