蛋白质/抗原/多肽 >> 重组蛋白
重组瘦素受体重叠转录基因1蛋白
半岛bd体育手机客户端 介绍
基因名:
LEPROTL1 半岛bd体育手机客户端 别名: HSPC112; Vps55; my047; LEPROTL1; leptin receptor overlapping transcript like 1; leptin receptor overlapping transcript like 1; leptin receptor overlapping transcript-like 1; endospanin-2; 瘦素受体重叠转录基因1; 背景信息:
Mutation of Ob (Obesity factor), also known as leptin precursor, results in profound obesity and type II diabetes as part of a syndrome that resembles morbid obesity in humans. The Ob gene product may function as a component of a signaling pathway in adipose tissue that functions to regulate body fat depot size. The leptin receptor, designated Ob-R, has been shown to be a single membrane-spanning receptor that most resembles the gp130 signal transducing component of the IL-6, G-CSF and LIF receptor. LEPROTL1 (Leptin receptor overlapping transcript-like 1) is a 131 amino acid multi-pass membrane protein that is highly homologous to the leptin receptor gene-related protein, Ob-R. LEPROTL1 is widely expressed and contains a JAK binding site. The LEPROTL1 gene is located on chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes.
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