蛋白质/抗原/多肽 >> 重组蛋白
重组类胰蛋白酶δ1
半岛bd体育手机客户端 介绍
基因名:
TPSD1 半岛bd体育手机客户端 别名: MCP7-LIKE; MCP7L1; MMCP-7L; TPSD1; tryptase delta 1; tryptase delta 1; tryptase delta; delta-tryptase; hmMCP-3-like tryptase III; mMCP-7-like delta II tryptase; mMCP-7-like-1; mMCP-7-like-2; mast cell tryptase; tryptase-3; 类胰蛋白酶δ1; 类胰蛋白酶δ1(TPSd1); 背景信息:
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008]
标签:His-tag |
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