蛋白质/抗原/多肽 >> 重组蛋白
重组T细胞和嗜酸性粒细胞表达特应性皮炎蛋白ETEA
半岛bd体育手机客户端 介绍
基因名：
FAF2 半岛bd体育手机客户端 别名： ETEA； UBXD8； UBXN3B； FAF2； Fas associated factor family member 2； Fas associated factor family member 2； FAS-associated factor 2； UBX domain containing 8； UBX domain protein 3B； UBX domain-containing protein 3B； UBX domain-containing protein 8； expressed in T-cells and eosinophils in atopic dermatitis； T细胞和嗜酸性粒细胞表达特应性皮炎蛋白ETEA； 背景信息：
ETEA is a 445-amino acid protein associated with atopic dermatitis (AD), a chronic noncontagious relapsing inflammatory skin disease characterized by eczematous skin lesions and also referred to as eczematous dermatitis. Other atopic diseases such as hay fever, asthma and conjunctivitis often occur along with AD. ETEA shows higher expression in T cells and eosinophils of patients with AD than in T cells and eosinophils of unaffected individuals. T cells are influential in the regulation of the inflammatory process of this disease. The persistence of jAD is attributed to dysregulated apoptosis in T cells, eosinophils, and keratinocytes. ETEA may be involved in the resistance to apoptosis in T cells and eosinophils of AD patients.
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