蛋白质/抗原/多肽 >> 重组蛋白
重组核受体共激活因子NCOA62蛋白
半岛bd体育手机客户端 介绍
基因名:
SNW1 半岛bd体育手机客户端 别名: Bx42; FUN20; NCOA-62; PRPF45; Prp45; SKIIP; SKIP; SKIP1; SNW1; SNW domain containing 1; SNW domain containing 1; SNW domain-containing protein 1; SKI interacting protein; homolog of Drosophila BX42; nuclear protein SkiP; nuclear receptor coactivator NCoA-62; nuclear receptor coactivator, 62-kD; ski-interacting protein; 核受体共激活因子NCOA62; 背景信息:
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. [provided by RefSeq, Jul 2008]
标签:His-tag |
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