蛋白质/抗原/多肽 >> 重组蛋白
重组着丝粒蛋白X
半岛bd体育手机客户端 介绍
基因名:
Cenpx 半岛bd体育手机客户端 别名: Stra13; Cenpx; centromere protein X; centromere protein X; centromere protein X; CENP-X; FANCM-interacting histone fold protein 2; Fanconi anemia-associated polypeptide of 10 kDa; immediate-early-response protein D9; retinoic acid-inducible gene D9 protein; stimulated by retinoic acid 13; stimulated by retinoic acid gene 13 protein homolog; 着丝粒蛋白X; 背景信息:
CENP-X is an 81 amino acid protein that functions as a DNA-binding component of the FA complex for genome maintenance and DNA damage repair. Localizing to chromatin in nucleus and centromere, Stra13 plays a role in muscle integrity by protecting muscle cells from oxidative damage, and Stra13 overexpression has been shown to produce oxidative damage resistance in mice. Stra13 undergoes alternative splicing events to produce three isoforms which are encoded by a gene that maps to human chromosome 17 and mouse chromosome 11. Stra13 plays a role in assembly of the outer kinetchore and is considered a target for myoepithelial cells and metastatic tumors.
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