试剂 半岛游戏平台官网入口网址 设备 原料
银牌会员第 1
访问量: 900090 网址:www.vuestras.com/show1001160 在线留言
半岛bd体育手机客户端 搜索
蛋白质/抗原/多肽 >> 重组蛋白
重组SH2B蛋白
重组SH2B蛋白图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Recombinant Sh2b1
Recombinant SH2B adaptor protein 1 protein
半岛bd体育手机客户端 介绍
基因名:

Sh2b1


半岛bd体育手机客户端 别名:

AI425885; C530001K22Rik; Irip; Psm; SH2-B; SH2-Bb; Sh2bpsm1; mKIAA1299; Sh2b1; SH2B adaptor protein 1; SH2B adaptor protein 1; SH2B adapter protein 1; SH2 domain-containing protein 1B; SH2-B PH domain containing signaling mediator 1; pro-rich, PH and SH2 domain-containing signaling mediator; SH2B蛋白;


背景信息:
Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways mediated by Janus kinase (JAK) and receptor tyrosine kinases, including the receptors of insulin (INS), insulin-like growth factor I (IGF1), nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), platelet-derived growth factor (PDGF) and fibroblast growth factors (FGFs). In growth hormone (GH) signaling, autophosphorylated ('Tyr-813') JAK2 recruits SH2B1, which in turn is phosphorylated by JAK2 on tyrosine residues. These phosphotyrosines form potential binding sites for other signaling proteins. GH also promotes serine/threonine phosphorylation of SH2B1 and these phosphorylated residues may serve to recruit other proteins to the GHR-JAK2-SH2B1 complexes, such as RAC1.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

相关半岛bd体育手机客户端
我要咨询 关闭
  • 姓名*
  • 电话*
  • 单位*
  • email
  • 留言内容*
  • 验证码*
  • 让更多商家关注
  • Baidu
    map