蛋白质/抗原/多肽 >> 重组蛋白
重组脑源性磷酸酶PTPN18蛋白
半岛bd体育手机客户端 介绍
基因名:
Ptpn18 半岛bd体育手机客户端 别名: FLP1; HSCF; PTP-HSCF; PTP-K1; Ptpk1; Ptpn18; protein tyrosine phosphatase, non-receptor type 18; protein tyrosine phosphatase, non-receptor type 18; tyrosine-protein phosphatase non-receptor type 18; FLP-1; fetal liver phosphatase 1; 脑源性磷酸酶PTPN18; 非受体型蛋白酪氨酸磷酸酶18(PTPN18); 背景信息:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
标签:His-tag |
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