鍩哄洜鍚嶏細

Pou2f3

浜у搧鍒悕锛欬p style="text-indent: 2em;">Epoc-1锛 Oct-11a锛 Oct11锛 Otf-11锛 Otf11锛 Skin锛 Skin-1a锛 Skn-1a锛 Skn-li锛 Pou2f3锛 POU domain, class 2, transcription factor 3锛 POU domain, class 2, transcription factor 3锛 POU domain, class 2, transcription factor 3锛 oct-11锛 octamer-binding protein 11锛 octamer-binding transcription factor 11锛 杞綍鍥犲瓙POU2F3锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]