蛋白质/抗原/多肽 >> 重组蛋白
重组I类组织相容性H-2抗原D-Dalpha链蛋白
半岛bd体育手机客户端 介绍
基因名：
H2-D1 半岛bd体育手机客户端 别名： H-2D； H2-D； H2-K1； H2-D1； histocompatibility 2, D region locus 1； histocompatibility 2, D region locus 1； H-2 class I histocompatibility antigen, D-B alpha chain； H-2D cell surface glycoprotein； H2-DC1-beta transplantation antigen protein； MHC H2-D-q alpha-chain； MHC class I H-2Dp； MHC class I H2 antigen； Q5k protein； I类组织相容性H-2抗原D-Dalpha链； 背景信息：
Predicted to enable several functions, including 14-3-3 protein binding activity; TAP binding activity; and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; negative regulation of neuron projection development; and positive regulation of T cell mediated cytotoxicity. Located in external side of plasma membrane. Colocalizes with membrane raft. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); eye disease (multiple); human immunodeficiency virus infectious disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A); HLA-B (major histocompatibility complex, class I, B); and HLA-C (major histocompatibility complex, class I, C). [provided by Alliance of Genome Resources, Apr 2022]
标签：His-tag |
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