蛋白质/抗原/多肽 >> 重组蛋白
重组G蛋白偶联受体GPR162蛋白
半岛bd体育手机客户端 介绍
基因名:
Gpr162 半岛bd体育手机客户端 别名: A-2; BC031437; Grca; Gpr162; G protein-coupled receptor 162; G protein-coupled receptor 162; probable G-protein coupled receptor 162; gene rich cluster, A; G蛋白偶联受体GPR162蛋白; 背景信息:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR162 is a 588 amino acid multi-pass membrane protein that functions as an orphan receptor and belongs to the GPR1 family. Existing as two alternatively spliced isoforms, the gene encoding GPR162 maps to human chromosome 12p13.31. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
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