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蛋白质/抗原/多肽 >> 重组蛋白
重组胰岛葡萄糖6磷酸酶2蛋白
重组胰岛葡萄糖6磷酸酶2蛋白图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Recombinant G6pc2
Recombinant glucose-6-phosphatase, catalytic, 2 protein
半岛bd体育手机客户端 介绍
基因名:

G6pc2


半岛bd体育手机客户端 别名:

G6pc-rs; IGRP; G6pc2; glucose-6-phosphatase, catalytic, 2; glucose-6-phosphatase, catalytic, 2; glucose-6-phosphatase 2; G-6-Pase 2; glucose-6-phosphatase, catalytic, related sequence; islet-specific glucose-6-phosphatase catalytic subunit-related protein; 胰岛葡萄糖6磷酸酶2;


背景信息:
Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-alpha, a second form, designated G6Pase-∫, contributes to blood glucose homeostasis in a wider range of tissues. Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), a homolog of the catalytic subunit of G6Pase, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites. The exact catalytic acivity of IGRP is not defined. Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects. Structurally, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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