蛋白质/抗原/多肽 >> 重组蛋白
重组细胞间粘附蛋白Vinexin
半岛bd体育手机客户端 介绍
基因名:
SORBS3 半岛bd体育手机客户端 别名: SCAM-1; SCAM1; SH3D4; SORBS3; sorbin and SH3 domain containing 3; sorbin and SH3 domain containing 3; vinexin; sorbin and SH3 domain-containing protein 3; vinexin beta (SH3-containing adaptor molecule-1); 细胞间粘附蛋白Vinexin; 背景信息:
Vinexin is a 671 amino acid protein that is expressed as two isoforms, designated Vinexin alpha and Vinexin beta. Localized to cell junctions in both the cytoplasm and the cytoskeleton, Vinexin alpha functions to promote Actin stress fiber formation, playing an important role in modification of the Actin cytoskeleton. Like Vinexin alpha, Vinexin beta is localized to cell junctions in the cytoplasm, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation. Although Vinexin alpha and Vinexin beta have different roles within the cell, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, including placenta, heart, liver, brain, pancreas and skeletal muscle. Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, signal transduction and cytoskeletal organization throughout the cell.
标签:His-tag |
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