半岛bd体育手机客户端 介绍
基因名：
B4GALT6 半岛bd体育手机客户端 别名： B4Gal-T6； beta4Gal-T6； B4GALT6； beta-1,4-galactosyltransferase 6； beta-1,4-galactosyltransferase 6； beta-1,4-galactosyltransferase 6； UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6； UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6； UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase； UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6； beta-1,4-GalTase 6； beta4GalT-VI； glucosylceramide beta-1,4-galactosyltransferase； lacCer synthase； lactosylceramide synthase； 背景信息：
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis. [provided by RefSeq, Jul 2008]
标签：His-tag |
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