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蛋白质/抗原/多肽 >> 重组蛋白
重组膜相关鸟苷酸反转激酶1蛋白
重组膜相关鸟苷酸反转激酶1蛋白图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Recombinant MAGI1
Recombinant membrane associated guanylate kinase, WW and PDZ domain containing 1 protein
半岛bd体育手机客户端 介绍
基因名:

MAGI1


半岛bd体育手机客户端 别名:

AIP-3; AIP3; BAIAP1; BAP-1; BAP1; MAGI-1; MAGI-1b; Magi1d; TNRC19; WWP3; MAGI1; membrane associated guanylate kinase, WW and PDZ domain containing 1; membrane associated guanylate kinase, WW and PDZ domain containing 1; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; BAI1-associated protein 1; WW domain-containing protein 3; atrophin-1-interacting protein 3; membrane-associated guanylate kinase inverted 1; trinucleotide repeat-containing gene 19 protein; 膜相关鸟苷酸反转激酶1;


背景信息:
The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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