鍩哄洜鍚嶏細

MBD4

浜у搧鍒悕锛欬p style="text-indent: 2em;">MED1锛 MBD4锛 methyl-CpG binding domain 4, DNA glycosylase锛 methyl-CpG binding domain 4, DNA glycosylase锛 methyl-CpG-binding domain protein 4锛 3,N(4)-ethenocytosine glycosylase锛 G/5-fluorouracil mismatch glycosylase with biphasic kinetics锛 G/T mismatch glycosylase锛 G/U mismatch glycosylase锛 methyl-CpG binding domain protein 4锛 methyl-CpG-binding endonuclease 1锛 methyl-CpG-binding protein MBD4锛 mismatch-specific DNA N-glycosylase锛 putative methyl-CpG binding protein锛 鐢插熀鍖朇pG缁撳悎铔嬬櫧MBD4锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]