半岛bd体育手机客户端 介绍
基因名：
MTMR3 半岛bd体育手机客户端 别名： FYVE-DSP1； ZFYVE10； MTMR3； myotubularin related protein 3； myotubularin related protein 3； myotubularin-related protein 3； FYVE (Fab1 YGLO23 Vsp27 EEA1 domain) dual-specificity protein phosphatase； FYVE domain-containing dual specificity protein phosphatase 1； phosphatidylinositol-3,5-bisphosphate 3-phosphatase； phosphatidylinositol-3-phosphate phosphatase； zinc finger FYVE domain-containing protein 10； zinc finger, FYVE domain containing 10； 肌微管素相关蛋白3； 背景信息：
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
标签：His-tag |
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