半岛bd体育手机客户端 介绍
基因名:
GPAA1 半岛bd体育手机客户端 别名: GAA1; GPIBD15; hGAA1; GPAA1; glycosylphosphatidylinositol anchor attachment 1; glycosylphosphatidylinositol anchor attachment 1; glycosylphosphatidylinositol anchor attachment 1 protein; GAA1 protein homolog; GPAA1P anchor attachment protein 1 homolog; GPI anchor attachment protein 1; GPI transamidase subunit; anchor attachment protein 1 (Gaa1p, yeast) homolog; glycophosphatidylinositol anchor attachment 1; glycosylphosphatidylinositol anchor attachment protein 1 homolog; 糖基磷脂酰肌醇锚连接蛋白1; 背景信息:
Glycosylphosphatidylinositol (GPI) acts as a membrane anchor for cell surface proteins. Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), also designated GPI anchor attachment protein 1 or GAA1 protein homolog, is a membrane protein localized to the endoplasmic reticulum which is involved in GPI-anchor biosynthesis. GPAA1 is crucial for GPI-anchoring of precursor proteins and catalyzes the attachment of GPI to proteins containing a C-terminal GPR attachment signal. GAA1 contains an N-terminal signal sequence, one cAMP- and cGMP-dependent protein kinase phosphorylation site, two potential N-glycosylation sites, one leucine zipper pattern and eight putative transmembrane domains. GPAA1 is ubiquitously expressed and shows higher levels of expression in fetal tissues than in adult tissues.
标签:His-tag |
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