蛋白质/抗原/多肽 >> 重组蛋白
重组锌指蛋白46
半岛bd体育手机客户端 介绍
基因名:
ZBTB25 半岛bd体育手机客户端 别名: C14orf51; KUP; ZNF46; ZBTB25; zinc finger and BTB domain containing 25; zinc finger and BTB domain containing 25; zinc finger and BTB domain-containing protein 25; zinc finger protein 46; zinc finger protein KUP; 锌指蛋白46; 背景信息:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 25 (ZBTB25), also known as ZNF46 or KUP, is a 435 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus and expressed mainly in hematopoietic cells and testis, ZBTB25 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB25 functions as a transcription regulator.
标签:His-tag |
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