蛋白质/抗原/多肽 >> 重组蛋白
重组甲基固醇羟化酶单加氧酶1蛋白
半岛bd体育手机客户端 介绍
基因名:
MSMO1 半岛bd体育手机客户端 别名: DESP4; ERG25; MCCPD; SC4MOL; MSMO1; methylsterol monooxygenase 1; methylsterol monooxygenase 1; methylsterol monooxygenase 1; C-4 methylsterol oxidase; sterol-C4-methyl oxidase; 甲基固醇羟化酶单加氧酶1; 背景信息:
Belonging to the sterol desaturase family, ERG25 is a 293 amino acid enzyme that performs the first of three enzymatic steps required to remove the two methyl groups leading to cholesterol. ERG25 is a multi-pass membrane protein that resides within the plasma membrane and the membrane of the endoplasmic reticulum. Concentrations of ERG25 mRNA increase when subjected to low iron growth conditions, suggesting that the enzyme is not regulated by iron but by an end product of the ergosterol pathway. Low-density lipoprotein (LDL) downregulates ERG25 expression in the vascular wall, an event that may be inhibited via SREBP overexpression. ERG25 is encoded by a gene located on human chromosome 4q32.3.
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