蛋白质/抗原/多肽 >> 重组蛋白
重组蛋白酪氨酸磷酸酶亩mu
半岛bd体育手机客户端 介绍
基因名：
PTPRM 半岛bd体育手机客户端 别名： PTPRL1； R-PTP-MU； RPTPM； RPTPU； hR-PTPu； PTPRM； protein tyrosine phosphatase receptor type M； protein tyrosine phosphatase receptor type M； receptor-type tyrosine-protein phosphatase mu； protein tyrosine phosphatase mu； protein tyrosine phosphatase, receptor type, mu polypeptide； 蛋白酪氨酸磷酸酶亩mu； 蛋白酪氨酸磷酸酶受体M(PTPRM)； 背景信息：
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]
标签：His-tag |
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