鍩哄洜鍚嶏細

PMM1

浜у搧鍒悕锛欬p style="text-indent: 2em;">PMM 1锛 PMMH-22锛 Sec53锛 PMM1锛 phosphomannomutase 1锛 phosphomannomutase 1锛 phosphomannomutase 1锛 brain glucose-1,6-bisphosphatase锛 纾烽吀鐢橀湶绯栧彉浣嶉叾1锛 纾烽吀鐢橀湶绯栭叾1(PMM1)锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.