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蛋白质/抗原/多肽 >> 重组蛋白
重组T淋巴细胞白血病同源蛋白2
重组T淋巴细胞白血病同源蛋白2图片
交货期: 1周
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交货期: 1周
半岛bd体育手机客户端 别名: Recombinant TLX2
Recombinant T cell leukemia homeobox 2 protein
半岛bd体育手机客户端 介绍
基因名:

TLX2


半岛bd体育手机客户端 别名:

HOX11L1; NCX; TLX2; T cell leukemia homeobox 2; T cell leukemia homeobox 2; T-cell leukemia homeobox protein 2; homeo box 11-like 1; homeobox protein Hox-11L1; neural crest homeobox protein; T淋巴细胞白血病同源蛋白2;


背景信息:
T-cell leukemia homeobox protein 2 (TLX2), also known as homeobox protein Hox-11L1 (HOX11L1), neural crest homeobox protein (NCX) or ENX, is a 284 amino acid member of the TLX homeobox family. The mouse homolog, Tlx2, has been detected in dorsal-root ganglia, cranial and entric-nerve gangla, parasympathetic ganglia and adrenal glands in mouse embryos and in the adrenal glands, intestine and heart of adult mice. The expression pattern of Tlx2, which is restricted to tissues derived from nerual crest cells, suggests that it may play a role in the proliferation or differentiation of the enteric peripheral nervous system. TLX2, which is localized to the nucleus, is highly homologous to mouse Tlx2, and shares several critical domains, including an enhancer element in the promotor that is crucial for tissue-specific expression. Mutations in the gene encoding mouse Tlx2 lead to congenital anomalies closely resembling neuronal intestinal dysplasia in humans. Thus, TLX2 is thought to play a role in this disease, which is a rare condition characterized by hyperplasia of submucosal plexus with giant submucosal ganglia and increased acetylcholinesterase activity in nerve fiber around submucosal blood vessels.

标签:His-tag
分类:Recombinant
类型:Protein
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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