蛋白质/抗原/多肽 >> 重组蛋白
重组G蛋白偶联受体γ3
半岛bd体育手机客户端 介绍
基因名:
GNG3 半岛bd体育手机客户端 别名: HG3D; GNG3; G protein subunit gamma 3; G protein subunit gamma 3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3; NBP gamma-3; guanine nucleotide binding protein (G protein), gamma 3; guanine nucleotide-binding protein gamma-3 subunit; heterotrimeric guanine nucleotide-binding protein 3D; G蛋白偶联受体γ3; 背景信息:
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (i.e. a photon, pheromone, odorant, hormone or neurotransmitter), while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein Alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the Beta subunits. It is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the Gamma as well as the Alpha and Beta subunits, and that preferential associations between members of subunit families increase G protein functional diversity.
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