蛋白质/抗原/多肽 >> 重组蛋白
重组巴尔得-别德尔综合征相关蛋白5
半岛bd体育手机客户端 介绍
基因名：
BBS1 半岛bd体育手机客户端 别名： BBS2L2； BBS1； Bardet-Biedl syndrome 1； Bardet-Biedl syndrome 1； Bardet-Biedl syndrome 1 protein； BBS2-like protein 2； 巴尔得-别德尔综合征相关蛋白5； 背景信息：
The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
标签：His-tag |
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