半岛bd体育手机客户端 介绍
靶标:
XAGE1B 半岛bd体育手机客户端 别名: CT12.1; CT12.1C; CT12.1D; CT12.1E; CT12.1b; CTP9; GAGED2; XAGE-1; XAGE1; XAGE1C; XAGE1D; XAGE1E; XAGE1B; X antigen family member 1B; X antigen family member 1B; X antigen family member 1; G antigen family D member 2; X antigen family member 1E; X antigen family, member 1C; X antigen family, member 1D; cancer/testis antigen 12.1; cancer/testis antigen family 12, member 1b; cancer/testis antigen family 12, member 1c; cancer/testis antigen family 12, member 1d; cancer/testis antigen family 12, member 1e; cancer/testis associated protein; protein XAGE-1; 背景信息:
XAGE1 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE1 is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. XAGE1 contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of XAGE1 generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites.
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