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钾离子通道多聚体结构域蛋白21抗体
半岛bd体育手机客户端 介绍
靶标：
KCTD21 半岛bd体育手机客户端 别名： KCASH2； KCTD21； potassium channel tetramerization domain containing 21； potassium channel tetramerization domain containing 21； BTB/POZ domain-containing protein KCTD21； potassium channel tetramerisation domain containing 21； potassium channel tetramerization domain-containing protein 21； 钾离子通道多聚体结构域蛋白21； 背景信息：
Swiss-Prot Acc.Q4G0X4.Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).
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