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杀菌/通透性增加蛋白样2抗体
半岛bd体育手机客户端 介绍
靶标:
BPIFC 半岛bd体育手机客户端 别名: BPIL2; BPIFC; BPI fold containing family C; BPI fold containing family C; BPI fold-containing family C protein; BPI-like 2; bactericidal/permeability-increasing protein-like 2; 杀菌/通透性增加蛋白样2; 背景信息:
Members of the bactericidal permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL2 (Bactericidal permeability-increasing protein-like 2) is a 507 amino acid secreted protein that contains the family??s common conserved feature of two cysteine residues that are critical for protein function. While BPIL2 is expressed in the basal layer of inflamed epidermis from psoriasis patients, it is not detected in normal skin.
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