抗体 >> 其他抗体
长寿相关基因lASS6抗体
半岛bd体育手机客户端 介绍
靶标：
Cers6 半岛bd体育手机客户端 别名： 4732462C07Rik； AW544719； Lass6； T1L； Cers6； ceramide synthase 6； ceramide synthase 6； ceramide synthase 6； LAG1 homolog, ceramide synthase 6； LAG1 longevity assurance homolog 6； longevity assurance homolog 6； sphingoid base N-palmitoyltransferase CERS6； 长寿相关基因lASS6； 背景信息：
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides.
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