抗体 >> 其他抗体
Rab7b抗体
半岛bd体育手机客户端 介绍
靶标：
Rab7b 半岛bd体育手机客户端 别名： 5430435G22Rik； Rab7b； RAB7B, member RAS oncogene family； RAB7B, member RAS oncogene family； ras-related protein Rab-7b； 背景信息：
Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN. Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
宿主：Rbt |
相关半岛bd体育手机客户端
|
