闈舵爣锛欬p style="text-indent: 2em;">Lclat1

浜у搧鍒悕锛欬p style="text-indent: 2em;">1-AGPAT 8锛 AI181996锛 Agpat8锛 Alcat1锛 Gm91锛 Lycat锛 Lclat1锛 lysocardiolipin acyltransferase 1锛 lysocardiolipin acyltransferase 1锛 lysocardiolipin acyltransferase 1锛 1-AGP acyltransferase 8锛 1-acylglycerol-3-phosphate O-acyltransferase 8锛 acyl-CoA:lysocardiolipin acyltransferase 1锛 蹇冪７鑴傞叞鍩鸿浆绉婚叾1锛

鑳屾櫙淇℃伅锛欬div style="text-indent: 2em;">LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.