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MAP激酶激活死亡域蛋白2C抗体
半岛bd体育手机客户端 介绍
靶标:
DENND2C 半岛bd体育手机客户端 别名: dJ1156J9.1; DENND2C; DENN domain containing 2C; DENN domain containing 2C; DENN domain-containing protein 2C; DENN/MADD domain containing 2C; RP5-1156J9.1; MAP激酶激活死亡域蛋白2C; 背景信息:
DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.
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