半岛bd体育手机客户端 介绍
靶标：
MARCHF10 半岛bd体育手机客户端 别名： MARCH-X； MARCH10； RNF190； MARCHF10； membrane associated ring-CH-type finger 10； membrane associated ring-CH-type finger 10； probable E3 ubiquitin-protein ligase MARCHF10； RING-type E3 ubiquitin transferase MARCH10； RING-type E3 ubiquitin transferase MARCHF10； membrane associated ring finger 10； membrane-associated RING finger protein 10； membrane-associated RING-CH protein X； membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase； probable E3 ubiquitin-protein ligase MARCH10； ring finger protein 190； testis secretory sperm-binding protein Li 228n； 环指蛋白190； 膜相关环指蛋白10； 背景信息：
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. MARCH10 (membrane-associated ring finger (C3HC4) 10), also known as RNF190 (ring finger protein 190) or MARCH-X, is an 808 amino acid protein with one RING-CH-type zinc finger domain. MARCH10 may function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation.
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