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GCOM1抗体
GCOM1抗体图片
交货期: 1周
索取资料及报价
交货期: 1周
半岛bd体育手机客户端 别名: Anti-GCOM1
Anti-GCOM1, MYZAP-POLR2M combined locus Antibody
半岛bd体育手机客户端 介绍
靶标:

GCOM1


半岛bd体育手机客户端 别名:

GRINL1A; Gcom2; MYZAP; MYZAP-POLR2M; gcom; GCOM1; GCOM1, MYZAP-POLR2M combined locus; GCOM1, MYZAP-POLR2M combined locus; GRINL1A combined protein; DNA-directed RNA polymerase II subunit GRINL1A; DNA-directed RNA polymerase II subunit M; GRINL1A combined protein Gcom12; GRINL1A complex locus 1; Glutamate receptor-like protein 1A; MYZAP-POLR2M readthrough; NMDAR1 subunit-interacting protein; glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A combined protein; myocardial zonula adherens protein;


背景信息:
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.

宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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