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α2-巨球蛋白样蛋白1(a2ML1)抗体
半岛bd体育手机客户端 介绍
靶标：
A2ML1 半岛bd体育手机客户端 别名： CPAMD9； OMS； p170； A2ML1； alpha-2-macroglobulin like 1； alpha-2-macroglobulin like 1； alpha-2-macroglobulin-like protein 1； C3 and PZP-like, alpha-2-macroglobulin domain containing 9； α2-巨球蛋白样蛋白1(a2ML1)； α2巨球蛋白样蛋白1α2ML1； 背景信息：
This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
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