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RAET1E抗体
半岛bd体育手机客户端 介绍
靶标:
RAET1E 半岛bd体育手机客户端 别名: LETAL; N2DL-4; NKG2DL4; RAET1E2; RL-4; ULBP4; bA350J20.7; RAET1E; retinoic acid early transcript 1E; retinoic acid early transcript 1E; retinoic acid early transcript 1E; NKG2D ligand 4; RAE-1-like transcript 4; UL16-binding protein 4; lymphocyte effector toxicity activation ligand; 背景信息:
The DCNP1 (dendritic cell nuclear protein 1) gene is specifically expressed in dendritic cells, potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response (1). It is localized mainly in the perinucleus. One of the alleles (A/T) of this gene causes premature translation termination at aa 117 and has been associated with an increased prevalence of major depression in humans (2,3). DCNP1 may play a role in the pathogenesis of depressive disorders by enhancing corticotropin-releasing hormone expression in the hypothalamic paraventricular nucleus (4).
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