抗体 >> 其他抗体
TRABD2A抗体
半岛bd体育手机客户端 介绍
靶标:
TRABD2A 半岛bd体育手机客户端 别名: C2orf89; TIKI1; TRABD2A; TraB domain containing 2A; TraB domain containing 2A; metalloprotease TIKI1; TRAB domain-containing protein 2A; UPF0632 protein C2orf89; 背景信息:
[FUNCTION] Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. [COFACTOR] Divalent metal cations. Manganese or cobalt.
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