首页 >> 半岛bd体育手机客户端
中心
抗体 >> 其他抗体
G蛋白偶联受体MRGX2蛋白抗体
半岛bd体育手机客户端
介绍 靶标: MRGPRX2 半岛bd体育手机客户端 别名: MGRG3; MRGX2; MRGPRX2; MAS related GPR family member X2; MAS related GPR family member X2; mas-related G-protein coupled receptor member X2; G protein-coupled receptor MRGX2; MAS-related GPR, member X2; Mas-related G protein-coupled receptor G3; G蛋白偶联受体MRGX2蛋白; 背景信息: function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion., 宿主:Rbt |
相关半岛bd体育手机客户端
|