半岛bd体育手机客户端 介绍
靶标:
CARD16 半岛bd体育手机客户端 别名: COP; COP1; LLID-114769; PSEUDO-ICE; CARD16; caspase recruitment domain family member 16; caspase recruitment domain family member 16; caspase recruitment domain-containing protein 16; CARD only domain-containing protein 1; CARD only protein; CARD-only protein 1; caspase recruitment domain-only protein 1; caspase-1 dominant-negative inhibitor pseudo-ICE; caspase-1 inhibitor COP; pseudo interleukin-1 beta converting enzyme; pseudo interleukin-1beta converting enzyme; pseudo-IL1B-converting enzyme; Caspase抑制剂COP蛋白; 背景信息:
Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
宿主:Rbt |
相关半岛bd体育手机客户端
|