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甲状腺受体相互作用蛋白8抗体
半岛bd体育手机客户端 介绍
靶标：
Jmjd1c 半岛bd体育手机客户端 别名： 5430433L24Rik； D630035I23Rik； Jmjdic； TRIP8； Jmjd1c； jumonji domain containing 1C； jumonji domain containing 1C； probable JmjC domain-containing histone demethylation protein 2C； jumonji domain-containing protein 1C； 甲状腺受体相互作用蛋白8； 背景信息：
The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants.
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