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13号染色体开放阅读框32抗体
半岛bd体育手机客户端 介绍
靶标:
Slain1 半岛bd体育手机客户端 别名: 9630044O09Rik; AA675320; AW742596; Slain1; SLAIN motif family, member 1; SLAIN motif family, member 1; SLAIN motif-containing protein 1; 13号染色体开放阅读框32; 背景信息:
SLAIN1 is a 561 amino acid member of the SLAIN motif-containing family and is expressed in embryonic stem cells, as well as in lung, brain and testis, where it exists as two alternatively spliced isoforms. The gene encoding SLAIN1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
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