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KBTBD8蛋白抗体
半岛bd体育手机客户端 介绍
靶标:
KBTBD8 半岛bd体育手机客户端 别名: TA-KRP; TAKRP; KBTBD8; kelch repeat and BTB domain containing 8; kelch repeat and BTB domain containing 8; kelch repeat and BTB domain-containing protein 8; T-cell activation kelch repeat protein; kelch repeat and BTB (POZ) domain containing 8; KBTBD8蛋白; 背景信息:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1 E3 ubiquitin ligase complex that acts as a regulator of neural crest specification. The BCR(KBTBD8 complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.
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