半岛bd体育手机客户端 介绍
靶标:
CHD9 半岛bd体育手机客户端 别名: AD013; CHD-9; CReMM; KISH2; PRIC320; CHD9; chromodomain helicase DNA binding protein 9; chromodomain helicase DNA binding protein 9; chromodomain-helicase-DNA-binding protein 9; ATP-dependent helicase CHD9; PPAR-alpha-interacting complex protein 320 kDa; PPAR{gamma}-interacting cofactor 320 kDa; chromatin remodeling factor CHROM1; chromatin-related mesenchymal modulator; ciprofibrate bound protein p240; kismet homolog 2; peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein; proteinx0008; ATP依赖的解螺旋酶; 背景信息:
function:Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis.,PTM:Phosphorylated on serine and tyrosine residues.,sequence caution:Wrong choice of frame.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,subunit:Interacts with PPARA. Probably interacts with ESR1 and NR1I3.,tissue specificity:Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.,
宿主:Rbt |
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