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嗜乳脂蛋白样8抗体
半岛bd体育手机客户端 介绍
靶标:
BTNL8 半岛bd体育手机客户端 别名: BTN9.2; BTNL8; butyrophilin like 8; butyrophilin like 8; butyrophilin-like protein 8; B7-H5 costimulatory molecule; 嗜乳脂蛋白样8; 背景信息:
BTNL8 is a 500 amino acid single-pass type I membrane protein that belongs to the immunoglobulin superfamily and contains one B30.2 SPRY domain and one Ig-like V-type (immunoglobulin-like) domain. Expressed as multiple alternatively spliced isoforms, BTNL8 is encoded by a gene which maps to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 comprises about 6% of human genomic DNA. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm on chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
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