半岛bd体育手机客户端 介绍
靶标：
CBLL1 半岛bd体育手机客户端 别名： HAKAI； RNF188； CBLL1； Cbl proto-oncogene like 1； Cbl proto-oncogene like 1； E3 ubiquitin-protein ligase Hakai； Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1； Cbl proto-oncogene like 1, E3 ubiquitin protein ligase； Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1； E-cadherin binding protein E7； RING finger protein 188； RING-type E3 ubiquitin transferase Hakai； c-Cbl-like protein 1； casitas B-lineage lymphoma-transforming sequence-like protein 1； 上皮钙粘附分子结合蛋白E7； 背景信息：
This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant.
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